What is the catalog number for Recombinant Human MTHFS (C-6His)?

The catalog number for Recombinant Human MTHFS (C-6His) is PEH1180.

What sizes are available for Recombinant Human MTHFS (C-6His)?

Recombinant Human MTHFS (C-6His) is available in the following size(s): 10 µg, 50 µg, 500 µg.

How many pack sizes does Recombinant Human MTHFS (C-6His) come in?

Recombinant Human MTHFS (C-6His) is available in 3 different pack sizes.

Is Recombinant Human MTHFS (C-6His) in stock?

Recombinant Human MTHFS (C-6His) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Recombinant Human MTHFS (C-6His)?

Recombinant Human MTHFS (C-6His) is requires dry ice shipping.

Recombinant Human MTHFS (C-6His)

Product Specifications

Background

5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion.

Product Name Alternative

5-formyltetrahydrofolate cyclo-ligase;5;10-methenyl-tetrahydrofolate synthetase; MTHFS; Methenyl-THF synthetase

Accession Number

P49914

Host

E.coli

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

24.3 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM Nacl, 1mM DTT, 50% Glycerol, pH 8.0.

Construct

Recombinant Human 5-formyltetrahydrofolate Cyclo-ligase is produced by our E.coli expression system and the target gene encoding Met1-Ala203 is expressed with a 6His tag at the C-terminus.