Recombinant Human MINPP1 (C-6His)

Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) . MINPP1 may play a role in bone development (endochondral ossification) .

Multiple Inositol Polyphosphate Phosphatase 1; 2;3-Bisphosphoglycerate 3-Phosphatase; 2;3-BPG Phosphatase; Inositol (1;3;4;5) -Tetrakisphosphate 3-Phosphatase; Ins (1;3;4;5) P (4) 3-Phosphatase; MINPP1; MIPP

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Leu487 is expressed with a 6His tag at the C-terminus.