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Recombinant Mouse MMP-12 (C-6His)

Product Specifications

Background

Matrix metalloproteinase-12 (MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1 site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

Product Name Alternative

Macrophage metalloelastase; MME; Matrix metalloproteinase-12; MMP-12; Mmp12; Mme; Mmel

Accession Number

P34960

Host

Human Cells

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

53 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/Protein/PHM1126_EnkiLife.pdf

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl,0.01%Tween80, 1mM EDTA, 50% Glycerol, pH6.0.

Construct

Recombinant Mouse Matrix Metalloproteinase 12 is produced by our Mammalian expression system and the target gene encoding Ala29-Cys473 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA for an activated form.

Species

Mouse

Available Sizes

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