Recombinant Human DTD1 (C-6His)

Product Specifications

Background

D-tyrosyl-tRNA (Tyr) deacylase 1 (DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA (Tyr) into D-tyrosine and free tRNA (Tyr), a possible defense mechanism against a harmful effect of D-tyrosine.

Product Name Alternative

D-tyrosyl-tRNA (Tyr) deacylase 1; DNA-unwinding element-binding protein B; DUE-B; Histidyl-tRNA synthase-related; DTD1; C20orf88; DUEB; HARS2

Accession Number

Q8TEA8

Host

Human Cells

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

24.5 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Construct

Recombinant Human D-tyrosyl-tRNA (Tyr) Deacylase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Pro209 is expressed with a 6His tag at the C-terminus.