Recombinant Human BDH2 (N-6His)

Product Specifications

Background

3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of 3-Hydroxybutyrate Dehydrogenase Type 2 make it suitable to conbert high levels of circulating 3-hydroxybutyrate into acetoacetate.

Product Name Alternative

3-Hydroxybutyrate Dehydrogenase Type 2; Dehydrogenase/Reductase SDR Family Member 6; Oxidoreductase UCPA; R-Beta-Hydroxybutyrate Dehydrogenase; BDH2; DHRS6

Accession Number

AAH01953.1

Host

E.coli

Endotoxin

<1 EU/µg as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Liquid

Molecular Weight

28.86 KDa

Shipping Conditions

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.

Construct

Recombinant Human 3-Hydroxybutyrate Dehydrogenase Type 2 is produced by our E.coli expression system and the target gene encoding Met1-Leu245 is expressed with a 6His tag at the N-terminus.