Recombinant Human ATG4A (N-6His)
Product Specifications
Background
Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
Product Name Alternative
Cysteine Protease ATG4A; AUT-Like 2 Cysteine Endopeptidase; Autophagin-2; Autophagy-Related Cysteine Endopeptidase 2; Autophagy-Related Protein 4 Homolog A; hAPG4A; ATG4A; APG4A; AUTL2
Accession Number
Q8WYN0
Host
E.coli
Endotoxin
<1 EU/µg as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE
Form
Liquid
Molecular Weight
47.5 KDa
Shipping Conditions
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Formulation
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Construct
Recombinant Human Autophagy Related 4 Homolog A is produced by our E.coli expression system and the target gene encoding Met1-Val398 is expressed with a 6His tag at the N-terminus.
Species
Human
Available Sizes
Frequently Asked Questions
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