Phleomycin
Phleomycin is a copper-dependent DNA damaging agent and antibiotic with antitumor activity. Phleomycin binds to DNA and produces ROS in the presence of reducing agents (such as dithiothreitol and glutathione), inducing single-strand and double-strand breaks in DNA. Phleomycin can induce cell apoptosis or mutation and is widely used in cancer inhibition, microbial genetic transformation (as a screening marker to improve fungal transformation efficiency) and DNA repair mechanism research[1][2][3].
Product Specifications
CAS Number
11006-33-0
UNSPSC
12352005
Hazard Statement
H302
Target
Antibiotic; Bacterial; DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/phleomycin.html
Purity
95.0
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[Phleomycin]
Precautions
H302
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Glycopeptide
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
GLT25D2 (COLGALT2) (NM_001303421) Human Over-expression Lysate
TRITC Conjugated Goat Polyclonal Antibody to Hamster IgG
