Phosphatidylinositol 4,5-bisphosphate
Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger[1][2][3].
Product Specifications
CAS Number
245126-95-8
Product Name Alternative
L-alpha-Phosphatidylinositol-4,5-bisphosphate
UNSPSC
12352211
Target
PI3K
Type
Natural Products
Related Pathways
PI3K/Akt/mTOR
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/phosphatidylinositol-4-5-bisphosphate.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(O)O[C@H]1[C@@H]([C@H]([C@@H](O)[C@@H](OP(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)(O)=O)[C@@H]1O)O)OP(O)(O)=O
Molecular Formula
C47H85O19P3
Molecular Weight
1047.09
References & Citations
[1]Katan M, et, al. Phosphatidylinositol (4,5) bisphosphate: diverse functions at the plasma membrane. Essays Biochem. 2020 Sep 23;64 (3) :513-531. |[2]Arreola J, et, al. Wasted TMEM16A channels are rescued by phosphatidylinositol 4,5-bisphosphate Cell Calcium. 2019 Dec;84:102103. |[3]Kato M, et, al. Arabidopsis PCaP2 modulates the phosphatidylinositol 4,5-bisphosphate signal on the plasma membrane and attenuates root hair elongation. Plant J. 2019 Aug;99 (4) :610-625.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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