D-erythro-MAPP
D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, with an IC50 of 1-5 μM in vitro[1].
Product Specifications
CAS Number
143492-38-0
Product Name Alternative
D-e-MAPP
UNSPSC
12352005
Target
Ceramidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-erythro-mapp.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC(CCCCCCCCCCCCC)=O
Molecular Formula
C23H39NO2
Molecular Weight
361.56
References & Citations
[1]Hüseyin İzgördü, et al. Characteristics of apoptosis induction in human breast cancer cells treated with a ceramidase inhibitor. Cytotechnology. 2020 Dec;72 (6) :907-919.|[2]A Bielawska, et al. (1S,2R) -D-erythro-2- (N-myristoylamino) -1-phenyl-1-propanol as an inhibitor of ceramidase. J Biol Chem. 1996 May 24;271 (21) :12646-54.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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