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C1qa polyclonal antibody

Product Specifications

Background

Involved in several processes, including complement-mediated synapse pruning; microglial cell activation; and nervous system development. Acts upstream of or within complement activation, classical pathway. Located in postsynapse. Is expressed in brain; foot; genitourinary system; and pancreas. Used to study epilepsy and systemic lupus erythematosus. Human ortholog (s) of this gene implicated in glomerulonephritis. Orthologous to human C1QA (complement C1q A chain) .

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

C1q; Adic; C1qa

Swiss Prot

P98086

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 23-245 of mouse C1qa (NP_031598.2) .

Conjugation

Unconjugated

Applications

WB, IHC-P, IF/ICC

Dilution

WB: 1:1000~1:5000 IHC-P: 1:500~1:1000 IF/ICC: 1:100~1:500

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

30KDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

C1qa polyclonal antibody detects endogenous levels of C1qa protein.

Applications Notes

Western blot analysis of various lysates using C1qa pAb at 1:2000 dilution.

Host or Source

Rabbit

Available Sizes

Curated Selection

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