CHRDL1 polyclonal antibody

Product Specifications

Background

Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity) . May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Chordin-like 1; CHL; MGC1; MGCN; VOPT; NRLN1; dA141H5.1

Swiss Prot

Q9BU40

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide of human CHRDL1

Conjugation

Unconjugated

Applications

WB, IHC-P

Dilution

WB: 1:500-1:1000 IHC-P: 1:50-1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .