γ-Aminobutyric acid

γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system[1][2].

Product Specifications

CAS Number

[56-12-2]

Product Name Alternative

4-Aminobutyric acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; GABA Receptor

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/_gamma_-Aminobutyric_acid.html

Purity

99.89

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(O)CCCN

Molecular Formula

C4H9NO2

Molecular Weight

103.12

Precautions

H302, H315, H319, H335

References & Citations

[1]Chen S, et al. Effects of dietary gamma-aminobutyric acid supplementation on the intestinal functions in weaning piglets. Food Funct. 2019 Jan 2.|[2]Okada R, et al. Gamma-aminobutyric acid (GABA) -mediated neural connections in the Drosophila antennal lobe. J Comp Neurol. 2009 May 1;514 (1) :74-91.