GLP-1 (7-36), amide (TFA)

GLP-1 (7-36), amide TFA is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells[1].

Product Specifications

Product Name Alternative

Glucagon-like peptide-1 (GLP-1) (7-36), amide (TFA) ; Human GLP-1 (7-36), amide (TFA)

UNSPSC

12352209

Target

GCGR

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glp-1-7-36-amide-tfa.html

Purity

98.59

Solubility

DMSO : ≥ 50 mg/mL|H2O : 5 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CC4=CNC5=CC=CC=C45)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC6=CNC=N6)N.OC(C(F)(F)F)=O.[x]

Molecular Formula

C149H226N40O45.xC2HF3O2

Molecular Weight

3297.63 (free base)

References & Citations

[1]Fujii Y et al. Ingestion of coffee polyphenols increases postprandial release of the active glucagon-like peptide-1 (GLP-1 (7-36) ) amide in C57BL/6J mice. J Nutr Sci. 2015 Mar 3;4:e9.