N-Hydroxypipecolic acid (potassium)

N-Hydroxypipecolic acid potassium (1-Hydroxy-2-piperidinecarboxylic acid potassium), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid potassium accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid potassium induces SAR to bacterial and oomycete infection[1][2][3].

Product Specifications

CAS Number

[2253632-01-6]

Product Name Alternative

1-Hydroxy-2-piperidinecarboxylic acid (potassium) ; NHP (potassium)

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/n-hydroxypipecolic-acid-potassium.html

Solubility

10 mM in DMSO

Smiles

O=C(C1N(O)CCCC1)O[K]

Molecular Formula

C6H10KNO3

Molecular Weight

183.25

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

References & Citations

[1]Shan L, et al. Pipped at the Post: Pipecolic Acid Derivative Identified as SAR Regulator. Cell. 2018 Apr 5;173 (2) :286-287.|[2]Ádám AL, et al. Signals of Systemic Immunity in Plants: Progress and Open Questions. Int J Mol Sci. 2018 Apr 10;19 (4) . pii: E1146.|[3]Hartmann M, et al. N-hydroxypipecolic acid and salicylic acid: a metabolic duo for systemic acquired resistance. Curr Opin Plant Biol. 2019 Aug;50:44-57.