MX69
MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment.
Product Specifications
CAS Number
[1005264-47-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E1/E2/E3 Enzyme; IAP; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MX69.html
Purity
99.60
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O=C(O)C1=CC=C(C2C(CC=C3)C3C(C=C(S(=O)(NC4=CC(C)=C(C)C=C4)=O)C=C5)=C5N2)C=C1
Molecular Formula
C27H26N2O4S
Molecular Weight
474.57
Precautions
H302, H315, H319, H335
References & Citations
[1]Gu L, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30 (4) :623-636|[2]Lubing Gu, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30 (4) :623-636
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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