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MX69

MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment.

Product Specifications

CAS Number

[1005264-47-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

E1/E2/E3 Enzyme; IAP; MDM-2/p53

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/MX69.html

Purity

99.60

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

O=C(O)C1=CC=C(C2C(CC=C3)C3C(C=C(S(=O)(NC4=CC(C)=C(C)C=C4)=O)C=C5)=C5N2)C=C1

Molecular Formula

C27H26N2O4S

Molecular Weight

474.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Gu L, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30 (4) :623-636|[2]Lubing Gu, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30 (4) :623-636

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-100892/MX69-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-100892/MX69-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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