AIMP2-DX2-IN-1
AIMP2-DX2-IN-1 (Compound 35) is a potent AIMP2-DX2 inhibitor with an IC50 of 0.1063 μM[1].
Product Specifications
CAS Number
[848256-17-7]
UNSPSC
12352005
Target
Aminoacyl-tRNA Synthetase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aimp2-dx2-in-1.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCC1OC(C=CC=C2)=C2OC1)CC3=CC=C(C=C3)C4=CC=CC=C4
Molecular Formula
C23H21NO3
Molecular Weight
359.42
References & Citations
[1]Lee B, et al. Discovery of benzodioxane analogues as lead candidates of AIMP2-DX2 inhibitors. Bioorg Med Chem Lett. 2022 Jul 13;73:128889.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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