Genevant CL1

Genevant CL1 (Lipid 10) is an ionizable lipid (pKa=6.3) . Genevant CL1 can be used for mRNA lipid nanoparticle (LNP) vaccine delivery[1][2].

Product Specifications

CAS Number

[1450888-71-7]

UNSPSC

12352211

Target

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/genevant-cl1.html

Concentration

10mM

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CN(C)CCCCC(OC(CCC/C=C\CCCCC)C(CCC/C=C\CCCCC)CCC/C=C\CCCCC)=O

Molecular Formula

C39H73NO2

Molecular Weight

588.00

References & Citations

[1]Michael D Buschmann, et al. Nanomaterial Delivery Systems for mRNA Vaccines. Vaccines (Basel) . 2021 Jan 19;9 (1) :65.|[2]Lam K, Leung A, Martin A, et al. Unsaturated, Trialkyl Ionizable Lipids are Versatile Lipid-Nanoparticle Components for Therapeutic and Vaccine Applications. Adv Mater. 2023;35 (15) :e2209624.