Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ivabradine (hydrochloride) (Standard)

Ivabradine hydrochloride (Standard) is the analytical standard of Ivabradine hydrochloride. This product is intended for research and analytical applications. Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If) . Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity[1][2][3][4].

Product Specifications

CAS Number

148849-67-6

UNSPSC

12352005

Target

HCN Channel; Reference Standards

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Cancer; Cardiovascular Disease; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ivabradine-hydrochloride-standard.html

Smiles

O=C1N(CCCN(C[C@@H]2C3=CC(OC)=C(OC)C=C3C2)C)CCC4=CC(OC)=C(OC)C=C4C1.Cl

Molecular Formula

C27H37ClN2O5

Molecular Weight

505.05

References & Citations

[1]Tardif JC, et al. Efficacy of ivabradine, a new selective I (f) inhibitor, compared with atenolol in patients with chronic stable angina. Eur Heart J. 2005 Dec;26 (23) :2529-36.|[2]Mulder P, et al. Heart rate slowing for myocardial dysfunction/heart failure. Adv Cardiol. 2006;43:97-105.|[3]Cavalcante TMB, et al. Ivabradine possesses anticonvulsant and neuroprotective action in mice. Biomed Pharmacother. 2019 Jan;109:2499-2512.|[4]Du XJ, et al. I (f) channel inhibitor ivabradine lowers heart rate in mice with enhanced sympathoadrenergic activities. Br J Pharmacol. 2004 May;142 (1) :107-12.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mucin 5AC (MUC5AC) (45M1), CF568 conjugate, 0.1mg/mL
BNC680031-100 1x 100 µL

Mucin 5AC (MUC5AC) (45M1), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Major Vault Protein (MVP) (1032), CF740 conjugate, 0.1mg/mL
BNC740225-100 1x 100 µL

Major Vault Protein (MVP) (1032), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
MCM7 (Proliferation Marker) (MCM7/1469), CF568 conjugate, 0.1mg/mL
BNC681469-500 1x 500 µL

MCM7 (Proliferation Marker) (MCM7/1469), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD1a (O10 + C1A/711), CF640R conjugate, 0.1mg/mL
BNC400717-100 1x 100 µL

CD1a (O10 + C1A/711), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD79a (JCB117 + HM47/A9), CF488A conjugate, 0.1mg/mL
BNC880828-500 1x 500 µL

CD79a (JCB117 + HM47/A9), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD34 (HPCA1/1171), CF740 conjugate, 0.1mg/mL
BNC741171-100 1x 100 µL

CD34 (HPCA1/1171), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details