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α-2,3-sialyltransferase-IN-1

α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is a noncompetitive α-2,3-sialyltransferase inhibitor with an IC50 of 6 μM.

Product Specifications

CAS Number

881179-06-2

Product Name Alternative

Lith-O-Asp analog

UNSPSC

12352211

Target

Sialyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/_alpha_-2,3-sialyltransferase-IN-1.html

Purity

98.0

Solubility

DMSO : ≥ 103.7 mg/mL

Smiles

C[C@@]1([C@@]2([H])[C@H](C)CCC(O)=O)[C@](CC2)([H])[C@@](CC[C@@]3([H])[C@@]4(CC[C@@H](OC([C@H](N)CC(O)=O)=O)C3)C)([H])[C@]4([H])CC1

Molecular Formula

C28H45NO6

Molecular Weight

491.66

References & Citations

[1]Chang KH, et al. Lithocholic acid analogues, new and potent alpha-2,3-sialyltransferase inhibitors. Chem Commun (Camb) . 2006 Feb 14; (6) :629-31.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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