α-2,3-sialyltransferase-IN-1
α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is a noncompetitive α-2,3-sialyltransferase inhibitor with an IC50 of 6 μM.
Product Specifications
CAS Number
[881179-06-2]
Product Name Alternative
Lith-O-Asp analog
UNSPSC
12352211
Target
Sialyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/_alpha_-2,3-sialyltransferase-IN-1.html
Purity
98.0
Solubility
DMSO : ≥ 103.7 mg/mL
Smiles
C[C@@]1([C@@]2([H])[C@H](C)CCC(O)=O)[C@](CC2)([H])[C@@](CC[C@@]3([H])[C@@]4(CC[C@@H](OC([C@H](N)CC(O)=O)=O)C3)C)([H])[C@]4([H])CC1
Molecular Formula
C28H45NO6
Molecular Weight
491.66
References & Citations
[1]Chang KH, et al. Lithocholic acid analogues, new and potent alpha-2,3-sialyltransferase inhibitors. Chem Commun (Camb) . 2006 Feb 14; (6) :629-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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