Arginase-2/ARG2, Human (His)

Arginase-2/ARG2 Protein, Human (His) expresses in E. coli with a His tag at the N-terminus. Arginase-2 (Arg2) acts as a fasting-induced hepatocyte factor that protects against hepatic and peripheral fat accumulation, hepatic inflammatory responses, and insulin and glucose intolerance in obese murine models[1].

HSVAVIGAPF SQGQKRKGVE HGPAAIREAG LMKRLSSLGC HLKDFGDLSF TPVPKDDLYN NLIVNPRSVG LANQELAEVV SRAVSDGYSC VTLGGDHSLA IGTISGHARH CPDLCVVWVD AHADINTPLT TSSGNLHGQP VSFLLRELQD KVPQLPGFSW IKPCISSASI VYIGLRDVDP PEHFILKNYD IQYFSMRDID RLGIQKVMER TFDLLIGKRQ RPIHLSFDID AFDPTLAPAT GTPVVGGLTY REGMYIAEEI HNTGLLSALD LVEVNPQLAT SEEEAKTTAN LAVDVIASSF GQTREGGHHH HHH

[1]Yiming Zhang, et al. Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting. Nat Commun. 2019 Apr 8;10(1):1587.