S- (+) -Marmesin
S- (+) -Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.
Product Specifications
CAS Number
[13849-08-6]
Product Name Alternative
(+) -Marmesin; (S) -Marmesin
UNSPSC
12352005
Hazard Statement
H302, H317
Target
COX; Lipoxygenase
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/S-__addition__-Marmesin.html
Concentration
10mM
Purity
99.9
Solubility
DMF : ≥ 100 mg/mL|DMSO : 2 mg/mL (ultrasonic) |Ethanol : 25 mg/mL (ultrasonic)
Smiles
O=C1C=CC2=CC3=C(O[C@H](C(C)(O)C)C3)C=C2O1
Molecular Formula
C14H14O4
Molecular Weight
246.26
Precautions
H302, H317
References & Citations
[1]Larbat R, et al. Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis. J Biol Chem. 2007 Jan 5;282 (1) :542-54. Epub 2006 Oct 26.|[2]Kim JS, et al. Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity. Arch Pharm Res. 2006 Aug;29 (8) :617-23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
5-LOX; COX-2
Available Sizes
Curated Selection
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