HDAC1/6-IN-2
HDAC1/6-IN-2 (I-c4) is the inhibitor of HDAC1 and HDAC6, with the IC50s of 3.1 nM and 2.95 nM, respectively. HDAC1/6-IN-2 has antitumor activity[1].
Product Specifications
UNSPSC
12352101
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac1-6-in-2.html
Smiles
O=C(C1=CC(C2=CC=C(C=C2)F)=CN3C1=NC=C3)NCC4=CC=C(C=C4)C(NO)=O
Molecular Formula
C22H17FN4O3
Molecular Weight
404.39
References & Citations
[1]Fei-Fei Yang, et al. Discovery of Novel Imidazo[1,2-a]pyridine-Based HDAC6 Inhibitors as an Anticarcinogen with a Cardioprotective Effect. J Med Chem. 2024 Aug 22;67 (16) :14345-14369.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC6
Frequently Asked Questions
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