Anti-IL-6 receptor [rhPM-1 (Tocilizumab) ]
Mouse monoclonal antibody to IL-6 receptor.
Product Specifications
Product Name Alternative
IL6R; IL-6R; CD126; MRA; atlizumab; TCZ; Interleukin-6 receptor subunit alpha; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; Membrane glycoprotein 80; gp80; PM1; PM-1
UniProt
P08887
Reactivity
Human
Immunogen
The original antibody was generated by CDR grafting of mouse PM-1 antibody onto human REI and NEW framework regions to create rhPM-1.
Target
IL-6 receptor
Clonality
Monoclonal
Clone
RhPM-1 (Tocilizumab)
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Concentration
1 mg/ml
Purity
Purified
References & Citations
Sato, K. et al. Humanization of a mouse anti-human interleukin-6 receptor antibody comparing two methods for selecting human framework regions Mol Immunol, 31, 371-381 (1994)
Pubmed id
8152440
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA
Host or Source
Human
Preservative
PBS with 0.02% Proclin 300.
Isotype
Human IgG
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