Propiverine-d7 (hydrochloride)
Product Specifications
Product Name Alternative
MSC2363318A
UNSPSC Description
Propiverine-d7 (hydrochloride) is the deuterium labeled Propiverine hydrochloride. Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence[1][2].
Target Antigen
Calcium Channel; Isotope-Labeled Compounds; mAChR
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling;Others
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(C(C1=CC=CC=C1)(C2=CC=CC=C2)OC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])OC3CCN(CC3)C.Cl
Molecular Weight
410.99
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Kitta T, et, al. Effects of propiverine hydrochloride, an anticholinergic agent, on urethral continence mechanisms and plasma catecholamine concentration in rats. Int Urogynecol J. 2013 Apr; 24(4): 683-8.|[3]Ito Y, et, al. Muscarinic Receptor Binding and Plasma Drug Concentration after the Oral Administration of Propiverine in Mice. Low Urin Tract Symptoms. 2010 Apr; 2(1):43-9.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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