(E) -UK122 (TFA)
(E) -UK122 TFA is the isomer of UK122 TFA. UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM[1].
Product Specifications
CAS Number
1186653-73-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
PAI-1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/e-uk122-tfa.html
Solubility
10 mM in DMSO
Smiles
N=C(C1=CC=C(/C=C2N=C(C3=CC=CC=C3)OC/2=O)C=C1)N.O=C(O)C(F)(F)F
Molecular Formula
C19H14F3N3O4
Molecular Weight
405.33
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Zhu M, et al. Identification of a novel inhibitor of urokinase-type plasminogen activator. Mol Cancer Ther. 2007;6 (4) :1348-1356.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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