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(E) -UK122 (TFA)

(E) -UK122 TFA is the isomer of UK122 TFA. UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM[1].

Product Specifications

CAS Number

1186653-73-5

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

PAI-1

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/e-uk122-tfa.html

Solubility

10 mM in DMSO

Smiles

N=C(C1=CC=C(/C=C2N=C(C3=CC=CC=C3)OC/2=O)C=C1)N.O=C(O)C(F)(F)F

Molecular Formula

C19H14F3N3O4

Molecular Weight

405.33

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Zhu M, et al. Identification of a novel inhibitor of urokinase-type plasminogen activator. Mol Cancer Ther. 2007;6 (4) :1348-1356.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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