CK1-IN-2
Product Specifications
UNSPSC Description
CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1].
Target Antigen
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ck1-in-2.html
Solubility
DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C1OCC2=NC=CC(C3=CN(C)N=C3C4=CC=C(F)C=C4)=C12
Molecular Weight
309.29
References & Citations
[1]Joris De Maeyer, et al. Casein kinase 1 inhibitors for use in the treatment of diseases related to dux4 expression such as muscular dystrophy and cancer. WO2020249717A1.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153866/CK1-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153866/CK1-IN-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1383376-92-8
Available Sizes
Curated Selection
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