Caffeic acid

Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO) .

Product Specifications

CAS Number

[331-39-5]

UNSPSC

12352005

Hazard Statement

H351

Target

Endogenous Metabolite; Lipoxygenase; TRP Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Caffeic_acid.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C/C1=CC=C(O)C(O)=C1

Molecular Formula

C9H8O4

Molecular Weight

180.16

Precautions

H351

References & Citations

[1]Pradhananga S, et al. Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice. Eur J Pharmacol. 2015 Sep 5;762:313-21.|[2]Liang G, et al. The protective effect of caffeic acid on global cerebral ischemia-reperfusion injury in rats. Behav Brain Funct. 2015 Apr 18;11:18.