What is the catalog number for Kaempferide?

The catalog number for Kaempferide is HY-15449.

What sizes are available for Kaempferide?

Kaempferide is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 50 mg.

How many pack sizes does Kaempferide come in?

Kaempferide is available in 4 different pack sizes.

Is Kaempferide in stock?

Kaempferide is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Kaempferide?

Kaempferide is manufactured by QuantiMol.

What is the estimated delivery time for Kaempferide?

Estimated delivery time for Kaempferide is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Kaempferide?

The safety data sheet for Kaempferide is available here: http://file.medchemexpress.com/batch_PDF/HY-15449/Kaempferide-SDS-MedChemExpress.pdf.

Kaempferide

Kaempferide is an orally active flavonol isolated from Hippophae rhamnoides L. Kaempferide has anticancer, anti-inflammatory, antioxidant, antidiabetic, antiobesity, antihypertensive, and neuroprotective activities. Kaempferide induces apoptosis. Kaempferide promotes osteogenesis through antioxidants and can be used in osteoporosis research[1][2][3][4][5][6].

Product Specifications

CAS Number

491-54-3

Product Name Alternative

Kaempferol 4'-O-methyl ether

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Akt; Apoptosis; Autophagy; Bacterial; Estrogen Receptor/ERR; FOXO; GSK-3; Influenza Virus; PI3K; β-catenin

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Autophagy; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/kaempferide.html

Concentration

10mM

Purity

99.80

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

O=C1C(O)=C(C2=CC=C(OC)C=C2)OC3=CC(O)=CC(O)=C13

Molecular Formula

C16H12O6

Molecular Weight

300.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Chandrababu G, et al. Kaempferide exhibits an anticancer effect against hepatocellular carcinoma in vitro and in vivo[J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 2023: 1-7.|[2]Tie F, et al. Kaempferol and kaempferide attenuate oleic acid-induced lipid accumulation and oxidative stress in HepG2 cells[J]. International Journal of Molecular Sciences, 2021, 22 (16) : 8847.|[3]Ma X, et al. Kaempferide enhances antioxidant capacity to promote osteogenesis through FoxO1/β-catenin signaling pathway[J]. European Journal of Pharmacology, 2021, 911: 174555.|[4]Tang H, et al. Kaempferide improves oxidative stress and inflammation by inhibiting the TLR4/IκBα/NF-κB pathway in obese mice[J]. Iranian Journal of Basic Medical Sciences, 2021, 24 (4) : 493.|[5]Wang D, et al. Kaempferide Protects against Myocardial Ischemia/Reperfusion Injury through Activation of the PI3K/Akt/GSK-3β Pathway. Mediators Inflamm. 2017;2017:5278218. |[6]Nath L R, et al. Kaempferide, the most active among the four flavonoids isolated and characterized from Chromolaena odorata, induces apoptosis in cervical cancer cells while being pharmacologically safe[J]. RSC advances, 2015, 5 (122) : 100912-100922.