4-Methyl-6-phenyl-2H-pyranone
4-Methyl-6-phenyl-2H-pyranone can be used for the synthesis of N-hydroxypyridone derivatives, which can protect astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality[1].
Product Specifications
CAS Number
[4467-30-5]
UNSPSC
12352005
Hazard Statement
H302, H319
Target
Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4-methyl-6-phenyl-2h-pyranone.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(C)C=C(C2=CC=CC=C2)O1
Molecular Formula
C12H10O2
Molecular Weight
186.21
Precautions
H302, H319
References & Citations
[1]Singh S, et al. Discovery of a novel series of N-hydroxypyridone derivatives protecting astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality. Bioorg Med Chem. 2017;25 (4) :1394-1405.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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