CID 1375606
CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27.
Product Specifications
CAS Number
[313493-80-0]
Product Name Alternative
Cyclopamine-KAAD
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Orphan GPCR; Orphan Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/CID_1375606.html
Purity
99.90
Solubility
DMSO : 53.33 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(C(NC2=CC=CC=C2)=O)C=C1)C3=CC=C(Cl)C=C3Cl
Molecular Formula
C20H14Cl2N2O2
Molecular Weight
385.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Dupuis N, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment. Mol Pharmacol. 2017 Jun;91 (6) :595-608.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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