Purified Anti-Human CD3 Antibody (OKT-3)
Product Specifications
Background
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.
Synonyms
CD3E| CD3e| T-cell surface antigen T3/Leu-4 epsilon chain| T-cell surface glycoprotein CD3 epsilon chain| T3E
Gene ID
916
UniProt
P07766
Host
Mouse
Reactivity
Human
Target
Human CD3
Clonality
Monoclonal
Isotype
IgG2a κ
Dilution
For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS, pH 7.2. Store at 2-8°C valid for 12 months, avoid freeze/thaw cycles.
Clone ID
OKT-3
Tested Applications
FC
Frequently Asked Questions
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