PPARGC1A antibody
Product Specifications
Background
PPARGC1A, also named as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, is a 798 amino acid protein, which Contains 1 RRM (RNA recognition motif) domain and localizes in the nucleus. PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. PPARGC1A can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism.
Synonyms
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha) |Ligand effect modulator 6|PPARGC1A|LEM6|PGC1|PGC1A|PPARGC1
Gene ID
10891
UniProt
Q9UBK2
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Target
PPARGC1A
Clonality
Monoclonal
Isotype
IgG1
Field of Research
Metabolism
Purification
Protein A affinity purified
Dilution
WB: 1:1000-1:10000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
110 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
21H1
Tested Applications
ELISA, WB
Immunogen Sequence
730-750aa
Curated Selection
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