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PPARGC1A antibody

Product Specifications

Background

PPARGC1A, also named as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, is a 798 amino acid protein, which Contains 1 RRM (RNA recognition motif) domain and localizes in the nucleus. PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. PPARGC1A can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism.

Synonyms

Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha) |Ligand effect modulator 6|PPARGC1A|LEM6|PGC1|PGC1A|PPARGC1

Gene ID

10891

UniProt

Q9UBK2

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Target

PPARGC1A

Clonality

Monoclonal

Isotype

IgG1

Field of Research

Metabolism

Purification

Protein A affinity purified

Dilution

WB: 1:1000-1:10000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

110 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

21H1

Tested Applications

ELISA, WB

Immunogen Sequence

730-750aa

Frequently Asked Questions

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