Phospho-p70 (S6K) (T389) /p85 (S6K) (T412) antibody
Product Specifications
Background
RPS6KB1 (Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway and it plays a key role in cell growth and proliferation by regulating insulin sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy. (PMID:22684641) . It has 2 isoforms produced by alternative initiation.
Synonyms
Ribosomal protein S6 kinase beta-1 (S6K-beta-1, S6K1) |70 kDa ribosomal protein S6 kinase 1 (P70S6K1, p70-S6K 1) |Ribosomal protein S6 kinase I|Serine/threonine-protein kinase 14A|p70 ribosomal S6 kinase alpha (p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA) |RPS6KB1|STK14A
Gene ID
6198
UniProt
P23443
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ribosomal protein S6 kinase, 70kDa, polypeptide 1
Target
RPS6KB1
Clonality
Polyclonal
Isotype
IgG
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70-85 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Curated Selection
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