APC Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody (RB6-8C5)

Product Specifications

Background

Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI) -linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

Synonyms

Gr-1| Gr1| Ly-6G/Ly-6C| Ly6G/Ly6C

Gene ID

546644 ,17067

UniProt

P35461, P0CW03

Host

Rat

Reactivity

Mouse

Target

Mouse Ly-6G/Ly-6C

Clonality

Monoclonal

Isotype

IgG2b κ

Conjugation

APC

Dilution

Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].

Form

Liquid

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

RB6-8C5

Tested Applications

Conjugation Information

APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter) .