Biotin-PEG4-PFP ester
Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1334172-58-5]
UNSPSC
12352203
Hazard Statement
H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biotin-peg4-pfp-ester.html
Purity
96.18
Solubility
10 mM in DMSO
Smiles
C(CCCC(NCCOCCOCCOCCOCCC(OC1=C(F)C(F)=C(F)C(F)=C1F)=O)=O)[C@H]2[C@@]3([C@](CS2)(NC(=O)N3)[H])[H]
Molecular Formula
C27H36F5N3O8S
Molecular Weight
657.65
Precautions
H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker
Available Sizes
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