FITC Anti-Mouse CD106 Antibody (M/K-2.7)

Product Specifications

Background

CD106 is a 110 kD glycosylphosphatidylinositol (GPI) -linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin) .

Synonyms

CD106| V-CAM 1| VCAM-1| Vascular cell adhesion protein 1| Vcam1

Gene ID

22329

UniProt

P29533

Host

Rat

Reactivity

Mouse

Target

Mouse CD106

Clonality

Monoclonal

Isotype

IgG1 κ

Conjugation

FITC

Dilution

Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].

Form

Liquid

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

M/K-2.7

Tested Applications

Conjugation Information

FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter) .