Biotin Anti-Mouse/Human CD11b Antibody (M1/70)
Product Specifications
Background
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Synonyms
CD11 antigen-like family member B| CD11b| CR-3 alpha chain| Integrin alpha-M| Itgam| Leukocyte adhesion receptor MO1
Gene ID
16409, 3684
UniProt
P05555, P11215
Host
Rat
Reactivity
Human/Mouse
Target
Mouse/Human CD11b
Clonality
Monoclonal
Isotype
IgG2b κ
Conjugation
Biotin
Dilution
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
M1/70
Tested Applications
FC
Available Sizes
Curated Selection
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