Biotin Anti-Human CD11a Antibody (TS1/22.1.1.13)
Product Specifications
Background
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .
Synonyms
CD11 antigen-like family member A| CD11a| Integrin alpha-L| Itgal| LFA-1A| Ly-15| Lymphocyte antigen 15
Gene ID
3683
UniProt
P20701
Host
Mouse
Reactivity
Human
Target
Human CD11a
Clonality
Monoclonal
Isotype
IgG1 κ
Conjugation
Biotin
Dilution
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
TS1/22.1.1.13
Tested Applications
FC
Available Sizes
Curated Selection
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