APC Anti-Mouse CD3 Antibody (17A2)
Product Specifications
Background
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Synonyms
CD3| CD3E/D/G/Z| CD3e/d/g/z| T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain
Gene ID
12502
UniProt
P04235, P11942, P22646, P24161
Host
Rat
Reactivity
Mouse
Target
Mouse CD3
Clonality
Monoclonal
Isotype
IgG2b κ
Conjugation
APC
Dilution
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
17A2
Tested Applications
FC
Conjugation Information
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter) .
Available Sizes
Curated Selection
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