PIK3CA antibody
Product Specifications
Background
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns (4, 5) P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.
Synonyms
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha, PI3K-alpha, PI3Kalpha, PtdIns-3-kinase subunit alpha) |Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha, p110alpha) |Phosphoinositide 3-kinase alpha|Phosphoinositide-3-kinase catalytic alpha polypeptide|Serine/threonine protein kinase PIK3CA|PIK3CA
Gene ID
5290
UniProt
P42336
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Phosphoinositide-3-kinase, catalytic, alpha polypeptide
Target
PIK3CA
Clonality
Monoclonal
Isotype
IgG2b
Field of Research
Signal Transduction
Purification
Protein A affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:100 - 1:500; IF:1:100-1:400
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
110 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
9B1
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
1-355aa
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