FITC Anti-Mouse CD226 Antibody (10E5)

Product Specifications

Background

CD226 (DNAM-1) is constitutively expressed on native CD8+ cells and on CD4+ T cells, macrophages and NK cells.This antibody (10E5) was reported to bind about 40% of inactivated CD4+ cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic encephalitis) mediated by Th1 cells.

Synonyms

DNAM-1|PTA1 (platelet and T cell activation antigen 1) |TLISA1|LFA-1 associated Molecule PTA-1

Gene ID

225825

UniProt

Q8K4F0

Host

Rat

Reactivity

Mouse

Target

Mouse CD226

Clonality

Monoclonal

Isotype

IgG2b κ

Conjugation

FITC

Dilution

Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) . Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Form

Liquid

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

10E5

Tested Applications

Conjugation Information

FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter) .