APC Anti-Human CD95/Fas Antibody (HFE7A/APO)
Product Specifications
Background
CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand) . CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
Synonyms
APT1|Apo-1 antigen|FAS1|FASLG receptor|TNFRSF6|Fas
Gene ID
355
UniProt
P25445
Host
Mouse
Reactivity
Human
Target
Human CD95/Fas
Clonality
Recombinant
Isotype
IgG2a κ
Conjugation
APC
Dilution
Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) . Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
HFE7A/APO
Tested Applications
FC
Conjugation Information
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter) .
Available Sizes
Curated Selection
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