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PE-Cy7 Anti-Human CD11c Antibody (BU15)

Product Specifications

Background

CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

Synonyms

CD11 antigen-like family member C|CD11c|Integrin alpha-X|Itgax|Leukocyte adhesion receptor p150+95

Gene ID

3687

UniProt

P20702

Host

Mouse

Reactivity

Human

Target

Human CD11c

Clonality

Monoclonal

Isotype

IgG1 κ

Conjugation

PE-Cy7

Dilution

Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) . Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Form

Liquid

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

BU15

Tested Applications

FC

Conjugation Information

PE-Cy7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter) .

Available Sizes

Curated Selection

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