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PE-Cy5.5 Anti-Human CD64 Antibody (10.1)

Product Specifications

Background

CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC) .

Synonyms

CD64|CD64A/B/C|FCGR1A/B/C|Fc fragment of IgG high affinity Ia/b/c receptor|Fc gamma RI|IGFR 1

Gene ID

2209

UniProt

P12314

Host

Mouse

Reactivity

Human

Target

Human CD64

Clonality

Monoclonal

Isotype

IgG1 κ

Conjugation

PE-Cy5.5

Dilution

Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) . Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Form

Liquid

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

10.1

Tested Applications

FC

Conjugation Information

PE-Cy5.5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 690 nm (e.g., a 690/50 nm bandpass filter) .

Available Sizes

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