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PE-Cy7 Anti-Human HLA-DR Antibody (L243)

Product Specifications

Background

HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

Synonyms

DRA/DRB1|HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain|HLA-DRA1/DRB1|MHC class II antigen DRA

Gene ID

3122, 3123

UniProt

P01903, P01911

Host

Mouse

Reactivity

Human

Target

Human HLA

Clonality

Monoclonal

Isotype

IgG2a κ

Conjugation

PE-Cy7

Dilution

Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) . Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Form

Liquid

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

L243

Tested Applications

FC

Conjugation Information

PE-Cy7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter) .

Available Sizes

Curated Selection

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