GSDME antibody
Product Specifications
Background
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms
Gasdermin-E|Inversely correlated with estrogen receptor expression 1 (ICERE-1) |Non-syndromic hearing impairment protein 5|Gasdermin-E, N-terminal (GSDME-NT) |Gasdermin-E, C-terminal (GSDME-CT) |GSDME|DFNA5|ICERE1
Gene ID
1687
UniProt
O60443
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Deafness, autosomal dominant 5
Target
GSDME
Clonality
Monoclonal
Isotype
IgG1
Field of Research
Neuroscience
Purification
Protein A+G purification
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
8A1
Tested Applications
ELISA, WB
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