Phospho-TAK1 (Thr187) antibody
Product Specifications
Background
MAP3K7 (Mitogen-activated protein kinase kinase kinase 7) is also named TAK1 and belongs to the MAP kinase kinase kinase subfamily. It plays an important role in the cascades of cellular responses evoked by changes in the environment. It has been linked to interleukin-1 receptor and tumor necrosis factor receptor signaling (PMID: 16186825) . It has 4 isoforms (53-55 kDa; 64-70 kDa and 75-80 kDa) produced by alternative splicing.
Synonyms
MAP3K7|TGF beta activated kinase 1|Mitogen-activated protein kinase kinase kinase 7|mitogen activated protein kinase kinase kinase 7|MAP3K 7
Gene ID
6885
UniProt
O43318
Host
Rabbit
Reactivity
Human
Immunogen
Peptide
Target
Phospho-TAK1 (Thr187)
Clonality
Polyclonal
Isotype
IgG
Field of Research
Cardiovascular, Metabolism, Developmental biology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:5000-1:20000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
WB
Immunogen Sequence
Peptide
Curated Selection
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